| SLOT | PLAYER | PROJ | PTS |
| QB | C.J. Stroud | 18.3 | -- |
| HOU QB · @CLE · Sun 1:00p |
| RB | Bijan Robinson | 16.8 | -- |
| ATL RB · vs KC · Sun 1:00p |
| RB | Audric Estime | 9.8 | -- |
| NO RB · vs CAR · Sun 1:00p |
| WR | Matthew Golden | 14.4 | -- |
| GB WR · vs MIN · Sun 1:00p |
| WR | Chris Olave | 12.7 | -- |
| NO WR · vs CAR · Sun 1:00p |
| TE | Hunter Henry | 7.5 | -- |
| NE TE · @DET · Sun 9:30a |
| FLEX | Jameson Williams | 10.1 | -- |
| DET WR · vs NE · Sun 9:30a |
| D/ST | 49ers D/ST | 4.5 | -- |
| SF D/ST · @DAL · Sun 4:25p |
| K | Brandon Aubrey | 10.5 | -- |
| DAL K · vs SF · Sun 4:25p |
| STARTERS | 104.6 | 0.0 |
| Bench | Kirk Cousins | 13.0 | -- |
| MIN QB · @GB · Sun 1:00p |
| Bench | Tre Tucker | 6.9 | -- |
| LV WR · vs SEA · Sun 4:05p |
| Bench | Kimani Vidal | 6.7 | -- |
| LAC RB · @BAL · Mon 8:15p |
| Bench | Vikings D/ST | 5.2 | -- |
| MIN D/ST · @GB · Sun 1:00p |
| Bench | A.J. Brown | 0.0 | -- |
| NE WR · @DET · Sun 9:30a |
| Bench | Colston Loveland | 0.0 | -- |
| CHI TE · BYE |
| Bench | Lamar Jackson | 0.0 | -- |
| BAL QB · vs LAC · Mon 8:15p |
| Bench | Kyle Monangai | 0.0 | -- |
| CHI RB · BYE |
| Bench | Bears D/ST | 0.0 | -- |
| CHI D/ST · BYE |
| BENCH | 31.7 | 0.0 |
| IR | Alec Pierce | 0.0 | -- |
| IND WR · vs MIA · Sun 1:00p |
| SLOT | PLAYER | PROJ | PTS |
| QB | Jayden Daniels | 18.7 | -- |
| WSH QB · @NYG · Thu 8:15p |
| RB | Derrick Henry | 17.5 | -- |
| BAL RB · vs LAC · Mon 8:15p |
| RB | Javonte Williams | 13.6 | -- |
| DAL RB · vs SF · Sun 4:25p |
| WR | J. Smith-Njigba | 18.5 | -- |
| SEA WR · @LV · Sun 4:05p |
| WR | Christian Watson | 12.9 | -- |
| GB WR · vs MIN · Sun 1:00p |
| TE | Kyle Pitts Sr. | 7.3 | -- |
| ATL TE · vs KC · Sun 1:00p |
| FLEX | Quinshon Judkins | 11.0 | -- |
| CLE RB · vs HOU · Sun 1:00p |
| D/ST | Ravens D/ST | 7.7 | -- |
| BAL D/ST · vs LAC · Mon 8:15p |
| K | Spencer Shrader | 10.6 | -- |
| IND K · vs MIA · Sun 1:00p |
| STARTERS | 117.9 | 0.0 |
| Bench | Bryce Young | 18.8 | -- |
| CAR QB · @NO · Sun 1:00p |
| Bench | Justin Herbert | 12.1 | -- |
| LAC QB · @BAL · Mon 8:15p |
| Bench | DJ Moore | 11.5 | -- |
| BUF WR · @NYJ · Sun 1:00p |
| Bench | Carnell Tate | 9.6 | -- |
| TEN WR · vs JAX · Sun 1:00p |
| Bench | Jordan Addison | 8.8 | -- |
| MIN WR · @GB · Sun 1:00p |
| Bench | Jordan Mason | 8.4 | -- |
| MIN RB · @GB · Sun 1:00p |
| Bench | Caleb Douglas | 7.6 | -- |
| MIA WR · @IND · Sun 1:00p |
| Bench | Dalton Schultz | 5.9 | -- |
| HOU TE · @CLE · Sun 1:00p |
| Bench | Steelers D/ST | 5.4 | -- |
| PIT D/ST · @CIN · Sun 8:20p |
| BENCH | 87.9 | 0.0 |
| IR | Romeo Doubs | 0.0 | -- |
| NE WR · @DET · Sun 9:30a |