| SLOT | PLAYER | PROJ | PTS |
| QB | Brock Purdy | 20.7 | -- |
| SF QB · @DAL · Sun 4:25p |
| RB | Jaylen Warren | 14.2 | -- |
| PIT RB · @CIN · Sun 8:20p |
| RB | Zach Charbonnet | 13.6 | -- |
| SEA RB · @LV · Sun 4:05p |
| WR | Nico Collins | 11.0 | -- |
| HOU WR · @CLE · Sun 1:00p |
| WR | Denzel Boston | 10.8 | -- |
| CLE WR · vs HOU · Sun 1:00p |
| TE | Travis Kelce | 9.0 | -- |
| KC TE · @ATL · Sun 1:00p |
| FLEX | Tutu Atwell | 7.5 | -- |
| LAR WR · @ARI · Sun 4:05p |
| D/ST | Bills D/ST | 6.2 | -- |
| BUF D/ST · @NYJ · Sun 1:00p |
| K | Jason Myers | 9.0 | -- |
| SEA K · @LV · Sun 4:05p |
| STARTERS | 102.1 | 0.0 |
| Bench | Jared Goff | 17.3 | -- |
| DET QB · vs NE · Sun 9:30a |
| Bench | Chase Brown | 11.1 | -- |
| CIN RB · vs PIT · Sun 8:20p |
| Bench | Corey Kiner | 9.7 | -- |
| NE RB · @DET · Sun 9:30a |
| Bench | Tyler Allgeier | 7.7 | -- |
| ARI RB · vs LAR · Sun 4:05p |
| Bench | D'Andre Swift | 0.0 | -- |
| CHI RB · BYE |
| Bench | David Montgomery | 0.0 | -- |
| HOU RB · @CLE · Sun 1:00p |
| Bench | Rome Odunze | 0.0 | -- |
| CHI WR · BYE |
| Bench | Courtland Sutton | 0.0 | -- |
| DEN WR · BYE |
| Bench | Mike Evans | 0.0 | -- |
| SF WR · @DAL · Sun 4:25p |
| BENCH | 45.8 | 0.0 |
| SLOT | PLAYER | PROJ | PTS |
| QB | Josh Allen | 24.3 | -- |
| BUF QB · @NYJ · Sun 1:00p |
| RB | Chuba Hubbard | 18.2 | -- |
| CAR RB · @NO · Sun 1:00p |
| RB | Breece Hall | 11.0 | -- |
| NYJ RB · vs BUF · Sun 1:00p |
| WR | Ja'Marr Chase | 18.6 | -- |
| CIN WR · vs PIT · Sun 8:20p |
| WR | Amon-Ra St. Brown | 16.4 | -- |
| DET WR · vs NE · Sun 9:30a |
| TE | Tyler Warren | 8.1 | -- |
| IND TE · vs MIA · Sun 1:00p |
| FLEX | Rachaad White | 9.7 | -- |
| WSH RB · @NYG · Thu 8:15p |
| D/ST | Jaguars D/ST | 6.4 | -- |
| JAX D/ST · @TEN · Sun 1:00p |
| K | Cam Little | 9.8 | -- |
| JAX K · @TEN · Sun 1:00p |
| STARTERS | 122.5 | 0.0 |
| Bench | Ashton Jeanty | 11.5 | -- |
| LV RB · vs SEA · Sun 4:05p |
| Bench | Chris Boswell | 10.5 | -- |
| PIT K · @CIN · Sun 8:20p |
| Bench | Deebo Samuel Sr. | 10.0 | -- |
| SF WR · @DAL · Sun 4:25p |
| Bench | Seahawks D/ST | 7.1 | -- |
| SEA D/ST · @LV · Sun 4:05p |
| Bench | Jordyn Tyson | 6.9 | -- |
| NO WR · vs CAR · Sun 1:00p |
| Bench | Devin Singletary | 6.3 | -- |
| NYG RB · vs WSH · Thu 8:15p |
| Bench | Brian Thomas Jr. | 5.4 | -- |
| JAX WR · @TEN · Sun 1:00p |
| Bench | Jaylen Waddle | 0.0 | -- |
| DEN WR · BYE |
| Bench | T. Henderson | 0.0 | -- |
| NE RB · @DET · Sun 9:30a |
| BENCH | 57.8 | 0.0 |
| IR | Tyreek Hill | 0.0 | -- |
| WR · BYE |